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[53] Ma XL, Ding Y, Wu L-M, et al

In the SAD portion of the Phase 1 study, VK2735 demonstrated promising safety and tolerability, as well as a predictable pharmacokinetic profile

Non-Alcoholic fatty liver disease and nutritional implications: special focus on copper

The postnatal effects as evaluated at 2 weeks of age, with 1 week of prior tamoxifen treatment, include growth retardation, disorganized growth plate, and reduced chondrocyte proliferation and differentiation

Gut barrier integrity is compromised

Combined with potential fluid losses from gastrointestinal side effects, dehydration and electrolyte imbalances can occur