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The STEP (Semaglutide Treatment Effect in People with obesity) trials, published in The New England Journal of Medicine , redefined expectations for metabolic care

Homer, R.J

Screening for binge eating disorder in obese outpatients

To reflect that, specific terms were introduced to describe apoptosis- and necroptosis-like cell deaths in enucleated cells: eryptosis and erythronecroptosis , respectively

In Phase 1 studies, survodutide was generally well tolerated, with no significant safety or tolerability issues observed in either healthy individuals with overweight or obesity [87, 88]

Heaney ML, Gardner JR, Karasavvas N, Golde DW, Scheinberg DA, Smith EA, et al