JM was supported by the NIH (R01DK114233, UG3DK142188, R01DK127497, R01DK138469), Breakthrough T1D (3-SRA-2023-1295-S-B, 3-SRA-2024-1555-S-B), Edward J
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Its compact four-amino acid structure facilitates straightforward handling across a broad range of in vitro experimental formats
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Before researchers discovered its vitaminic properties, the British chemist Alexander Wynter Blyth observed the presence in milk of a yellow-green fluorescent pigment in the 1870s, which was later found in eggs, liver, beer yeast, and fruits, resulting in various names such as lactoflavin, ovoflavin, hepatoflavin, among others [2]