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For now, injectable options like semaglutide, prescribed when medically appropriate by a licensed provider, remain the gold standard in GLP-1 treatment

Its shape now looks like a tube, banana or sleeve that restricts the amount of food consumption

More real-world comparisons are needed to determine whether this would be more effective than semaglutide, said Mir Ali, MD, medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA

(Source: Drugs.com, May 2026) A related risk worth naming: Nausea during titration can cause patients to under-eat protein specifically, which compounds lean mass loss

Without insurance, brand-name Contrave can run $250$400+ per month

The oral switch data is also important