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The Donezipil study attempted to repair a specific cholinergic deficit in the brain the Japanese believed was caused by HHV-6 reactivation

Salton F, Ruaro B, Confalonieri P, Confalonieri M (2020) Epithelial-mesenchymal transition: a major pathogenic driver in idiopathic pulmonary fibrosis

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A key pharmacological consideration is ashwagandhas interaction with the GABAergic system