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She notes that ingredients like high concentrations of glycolic acid, fragrance, and certain essential oils are more likely to cause irritation, so if your skin tends to react easily, start slowly and look for formulas that pair brightening ingredients with barrier-supportive hydrators and soothing ingredients rather than going all-in on intensive exfoliation

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Pigment Cell Res 1, 386389 (1988)

As for the medications themselves, the physical side effects are pretty well known: nausea and other G.I

trade name: Poncho Votivo) and a pyrethroid (primary active ingredient: esfenvalerate