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(H) Volcano plot showing the hypergeometric distribution analysis of the CRISPR/Cas9 small-scale screen in BoMac
While with the presence of gingipain inhibitors which can reduce the activity of the gingipain enzyme, a significant reduction of soluble UA release at or near the control levels could be observed (91)
Importantly, serum glucagon levels were significantly lower in AAV-sh-VGF-injected mice compared to controls (Fig
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