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By 48 weeks, significant average weight loss was seen at all maintenance doses: With longer treatment lasting up to 68 weeks, weight loss continued, particularly at higher doses: 12mg: average weight loss of up to 28.7% of body weight This longer-term data shows that weight loss with retatrutide can continue beyond one year, rather than plateauing early, especially at higher maintenance doses
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A similar study noted that ipamorelin administration in female rats resulted in increased bone mineral content, which is suggestive of stronger, denser bones [5]
Life Extension also keeps things simple with a one-capsule serving that provides 600mg of NAC