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The interval exists to give the body time to adapt and the provider time to judge

doi: 10.1146/annurev-biochem-083024-110827

Tsukuda, Journal of the American Chemical Society 127, (2005) 52615270

However, it is not known whether supplemental intake of these nutrients would result in additional benefits

This difference matters significantly when considering combination therapy, because pairing a medication that triggers insulin with one that improves insulin sensitivity can create compounding effects on your glucose levels