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doi: 10.1158/2159-8290.CD-19-1500 35 FengHStockwellBR

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Under no circumstances are these products approved or intended for human or veterinary consumption, direct clinical diagnostics, or therapeutic drug administration

Additionally, if berberine significantly alters gut bacteria composition, this could theoretically affect bowel regularity in either direction, though this mechanism remains speculative

Products like psyllium (Metamucil) or methylcellulose can be helpful for both IBS-C (for constipation) and IBS-D (they can bind somewhat to loose stool)

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