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Moreover, within the biological process category, cellular process, regulation of biological process, and biological regulation were identified as key processes

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Fibrosis A major contributor to kidney fibrosis is the epithelial-to-mesenchymal transition (EMT), primarily regulated by the TGF-/SMAD signaling pathway and hypoxia (Sohn et al

Biochemical investigations showed a normal level of cysteinyl glycine in plasma, an abnormal urinary profile with increased excretion of cysteinyl glycine (4972 mmol/mol of creatinine) and leukotrienes with increased leukotriene D4 and complete absence of LTE4

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