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doi: 10.2337/diabetes.53.3.654 34 DeaconCFPridalLKlarskovLOlesenMHolstJJ

[1] This abnormal keratinization and skin cell proliferation combined with down-regulating 5-Reductase (due to insufficient IGF-1) [19] eventually atrophies the sebaceous glands by reducing sebocyte proliferation that would typically be induced by DHT, if not for the loss of 5-Reductase regulation from IGF-1

Curr Drug Abuse Rev 2010;3:163174.ArticlePubMedPMC 72

[15] leveraged CRISPR screening of gene and environment interactions to demonstrate buffering interactions between SLC25A39 and the mitochondrial iron transporter SLC25A37, revealing SLC25A39 as a candidate and further supported by in vitro metabolomics and GSH transport experiments

For example, Bose et al