Route/evidence mismatch: the pivotal mouse study tested subcutaneous injection at a fixed research dose (20 mg/kg, three times daily) the oral capsule use that is actually sold and discussed commercially has not itself been directly tested in that published research
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Injections bypass the gut, ensuring the body utilizes the full dose
According to Harvard Medical School, people with cobalamin deficiency may experience subtle but unusual and progressive signs of illness, including strange tingling or numb sensations, difficulty walking, cognitive and memory issues, and weakness
doi:10.1126/science.125.3253.884
Donor treatment with a PHD-inhibitor activating HIFs prevents graft injury and prolongs survival in an allogenic kidney transplant model