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The progression to dual agonists represented by tirzepatide (GLP-1 + GIP) demonstrated that targeting additional metabolic receptors could significantly amplify research outcomes

GLP-1 is short for glucagon-like peptide-1 receptor agonists, and it's a type of medication that's usually prescribed for diabetes, but is also used for weight management

It acts directly on neighboring -cells to inhibit the secretion of glucagon and can also indirectly influence -cells by inhibiting the secretion of other hormones

The other group was prescribed a diabetes medication but did not use any GLP-1 drugs

The upper bound of this confidence interval, 1.03, excluded the pre-specified non-inferiority margin of 1.3

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