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Quantitative analysis of LC3 positive puncta per cell was performed by counting at least 150 cells for each condition

Semaglutide slows how quickly food moves from your stomach to your small intestine, which gives your digestive system more time to work with available bile

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Mean change in HbA1c from baseline at week 40 was -22 percentage points with semaglutide 20 mg and -19 percentage points with semaglutide 10 mg (estimated treatment difference [ETD] -023 percentage points [95% CI -036 to -011]

The durability of results confirms that semaglutide appetite suppression is sustained over extended treatment periods, which matters for people evaluating how long to stay on semaglutide