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In an ischemic pig kidney, 5 or 10 mg/kg of trimetazidine given intravenously significantly reduced CD4+ lymphocytes [159]

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These results indicate that treatment with GABA, DSIP-CBBBP and more effectively reduced wakefulness time, with DSIP-CBBBP showing the most substantial reduction, suggesting its potential as a therapeutic agent for mitigating insomnia