George Choose from physician-guided semaglutide and tirzepatide treatment options, including compounded medication when clinically appropriate and FDA-approved brands such as Wegovy and Zepbound
Most patients can safely continue GLP-1 medications before colonoscopy with appropriate precautions, including a 24-hour liquid-only diet before the procedure
TRIUMPH-4, the first completed Phase 3 trial, showed 28.7% average body weight loss at 68 weeks on retatrutide 12mg versus 2.1% on placebo, as reported by Eli Lilly in December 2025 (peer-reviewed publication pending)
Compounded versions using the same active pharmaceutical ingredient are not FDA-approved as finished dosage forms
The drug beat analysts expectations of $2.3 billion, according to a consensus estimate from FactSet
If youre experiencing nausea or diarrhea, increase your fluid intake accordingly to maintain proper fluid and electrolyte balance