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During active side effects from your last dose If you are still experiencing significant nausea, vomiting, or other side effects from your most recent injection, do not inject early

Stupnisek, M., Kokot, A., Drmic, D., et al

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70,71 Additionally, ASOs can form a double-stranded structure complementary to miRNA, leading to its degradation and causing gene upregulation

Human studies in ulcerative colitis in 2002 and 2005 showed clinically meaningful results with an excellent safety profile