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You may recognize some of the most common GLP-1 drugs by name: Semaglutide: Sold under the brand names Ozempic, Wegovy and Rybelsus Liraglutide: Marketed as Victoza and Saxenda Tirzepatide: Known as Mounjaro and Zepbound While originally developed for diabetes and weight management, GLP-1s may also have effects on the brain and nervous system

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It is widely recognised that metformin improves glycaemic control with a good safety profile, weight neutrality or weight loss, lack of associated hypoglycaemia, reduced cardiovascular mortality and low cost [3]

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