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mTORC2 regulates amino acid metabolism in cancer by phosphorylation of the cystine-glutamate antiporter xCT

Robert Kushner: Yeah, great question

In the STEP 1 trial , 1,961 adults with a BMI of 30 or higher (or 27 with weight-related health conditions) took weekly doses of Semaglutide 2.4 mg for 68 weeks