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Notably, FMT has confirmed effectiveness in treating various conditions, including recurrent Clostridium difficile infection (254), inflammatory bowel disease (255), and irritable bowel syndrome (256)
This mechanistic insight has prompted the exploration of ferroptosis as a therapeutic target, given its potential contribution to dopaminergic neuronal loss and disease progression
10.1016/j.neuint.2014.02.008 90 ParsonsA
GLP-1s are highly effective for most people, but they also have some serious risks
The mechanism operates through upstream modulation of inhibitor of kappa B (IkB) kinase activity, which normally phosphorylates and degrades IkB proteins, freeing NF-kB to drive inflammatory gene transcription