These skin lightening treatments work by reducing the amount of melanin in the skin, which is responsible for the skins colour
While GHK-Cu skin benefits are well-documented, some users report temporary irritation or breakouts, especially if used with incompatible products
We have solved the structures of the pi class GST hP1-1 in complex with its substrate, glutathione, a transition-state complex, the Meisenheimer complex, and an inhibitor, S-(rho-bromobenzyl)-glutathione, and refined them to resolutions of 1.8 A, 2.0 A and 1.9 A, respectively
Avoid repeated freeze-thaw cycles of reconstituted solutions, as temperature fluctuations may lead to peptide degradation and reduced biological activity
The combined model presented here effectively extends the work of Reed et al
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