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We observed no significant inhibition of UGT1A1 or other transporters for SEP-479 and no hyperbilirubinemia in any of the non-clinical studies to date for SEP-479, including the 7-day and 28-day GLP toxicology studies in healthy cynomolgus monkeys
and Edward DAlessandro, Jr
Published research has documented GHK-Cus anti-fibrotic effects in intestinal models, relevant to IBD and gut permeability research
MicroRNA29a treatment improves early tendon injury
Of note, inactivation of the genes encoding DIOs in rodent models has revealed a role for DIO type 1 in iodine homeostasis and the importance of DIOs type 2 and 3 in the maturation of auditory and visual systems during fetal development (10)
