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Translating these findings into human populations, NRI is examining how GLP-1 modulation influences craving intensity, relapse vulnerability, emotional stability, cognitive performance, and quality of life among individuals diagnosed with opioid use disorder

3D-cultured GIC spheres were embedded into paraffin blocks according to a slightly modified protocol 38 , subsequently sectioned and subjected to standard staining procedures as specified above

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Transmission electron microscopy (TEM) imaging of OsO 4 -postfixed HEK293T cells showed that surface LaccID provides excellent contrast at the plasma membrane, with minimal staining of intracellular membranes on the ER, mitochondria and nucleus (Fig