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The total weight loss at 12 months for most people falls between 15 and 22% of starting body weight

The SUSTAIN and SURMOUNT trial programs for branded drugs showed 15-20% weight reduction in study populations over 68-72 weeks

Some emerging research has explored potential connections between GLP-1 signalling and thyroid function

Neuroprotective effects of a triple GLP-1/GIP/glucagon receptor agonist in the APP/PS1 transgenic mouse model of Alzheimers disease

Contact your healthcare provider immediately if you experience symptoms such as severe abdominal pain (especially radiating to the back), persistent vomiting, signs of an allergic reaction (rash, difficulty breathing, swelling), or symptoms of low blood sugar

[DOI] [PubMed] [Google Scholar] 66.Mondragon A, Davidsson D, Kyriakoudi S, Bertling A, Gomes-Faria R, Cohen P, Rothery S, Chabosseau P, Rutter GA, da Silva Xavier G