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Surprisingly, deletion of PNPLA2 does not result in obesity, likely due to counter-regulatory mechanisms such as reductions in food intake and reduced PPAR signaling in adipose tissue (239)

Insurers declined coverage for obesity treatments, writing them off as cosmetic. As a result, pharmaceutical research into obesity drugs was underfunded, underappreciated, and often doomed

Medical teams focus on reducing inflammation and preventing complications through specific treatments based on how severe the condition is

Miyamoto K, Nguyen KT, Allen GE, et al

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