What was once a stepwise sequence: metformin, sulfonylurea, insulin: has become a personalised choice, with classes (GLP-1 receptor agonists, SGLT2 inhibitors, dual GIP/GLP-1 agonists) chosen as much for cardiovascular and renal protection as for blood-glucose control
According to research , it is a good source of inulin, promoting the growth of beneficial gut bacteria
PLoS One 6:e18250
Nutrient timing and meal structure When you can only eat two or three meals a day because your appetite has been crushed by a triple agonist, every meal needs to count
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Dosing convenience also plays a role in adherence