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Effect of a specific glucose-dependent insulinotropic polypeptide receptor antagonist in the rat

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Overall, we think that the orange fruit extract is a very complex ingredient with lots of potentially good things in it, but we could not find proper in-vivo (made on real people) studies made with standardized extracts to validate what it really does or does not under real-world use cases

As expected, GLP-1R agonism resulted in a reduced intake of both control liquid and ethanol diets, and a corresponding reduction of body weight in both the control and ethanol groups (Supplementary Fig