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While ROS scavenging is beneficial in chronic diseases like diabetes (Zhang et al., 2020), excessive antioxidant supplementation may disrupt redox homeostasis, as evidenced by increased cancer risk in vitamin E trials ( Antioxidants, which include both enzymatic (e.g., SOD, CAT) and non-enzymatic agents (e.g., ALA, polyphenols), counteract ROS by restoring redox balance and modulating inflammatory and apoptotic pathways

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I describe the diagnostic criteria that distinguish bipolar I from bipolar II, including mania and hypomania and the different patterns of mood cycling

It is commonly used in controlled laboratory experiments analyzing endocrine signaling pathways and receptor activation