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On the data side, the Lau phase 2 obesity trial showed Cagrilintide monotherapy producing dose-related weight loss, reaching close to 10.8 percent at the top dose over roughly 26 weeks, against about 3 percent on placebo

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This review evaluates the therapeutic potential of GM-targeted interventions, including probiotics, prebiotics, and fecal microbiota transplantation, and underscores the GM as a pivotal therapeutic target, emphasizing that future therapeutic strategies for OP must incorporate the interconnected GM-bone axis for efficacious prevention and treatment

doi: 10.1038/s41598-023-27405-w 75 HaoFTamWHuXTanWJiangLJiangXet al

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94 , e02015-19 (2020)