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These different types of stressors formed the basis of establishing the chronic mild stress (CMS) model in rodents 22

For a middle-aged patient with creeping weight gain and a family history of heart disease, starting oral semaglutide can be the decisive factor that prevents a future heart attack

In the recent exenatide trial [34], the difference in weight loss between the exenatide and placebo groups was 0.5 kg, which is lower than the 2.0 kg difference observed in a previous randomised trial [32]

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Sleep deprivation impairs leptin signaling and increases hunger hormones, so prioritizing 79 hours per night can unlock additional progress

Mechanism: Reduce repetitive firing of neurons by stabilizing inactive sodium channels