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Abrupt cessation after prolonged use can result in temporary GH deficiency symptoms including fatigue, poor recovery, and sleep disturbances lasting 612 weeks

Additionally, ROS can promote the recruitment and activation of immunosuppressive cells, such as regulatory T cells (Tregs) and myeloid-derived suppressor cells (MDSCs), which further inhibit the anti-tumor immune response and facilitate tumor progression [123]

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10.1074/jbc.M211596200