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Mantovani G, Isidori AM, Moretti C, Di Dato C, Greco E, Ciolli P et al (2019) Selenium supplementation in the management of thyroid autoimmunity during pregnancy: results of the SERENA study, a randomized, double-blind, placebo-controlled trial

Due to multiple comparisons (12 metals), only p-values below 0.004 should be considered significant, and p values between 0.05 and 0.004 should be considered marginally significant

By disrupting the interaction between FOXO4 and p53, FOXO4-DRI induces apoptosis (programmed cell death) in senescent cells, reducing their harmful effects

doi:10.1016/0003-2697(79)90188-x

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