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What GLP-1 Medications Do GLP-1 (glucagon-like peptide-1) is a hormone naturally produced in the gut after eating

They do this by decreasing the activity of the protein breakdown pathway, and also by decreasing the expression of several complexes involved in protein breakdown

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Possible drug interactions with Onglyza include: Other oral diabetes medications, such as Ozempic (semaglutide) and Novolog (insulin aspart) Drinking alcohol while taking Onglyza can increase the risk of high blood sugar (hyperglycemia) and low blood sugar (hypoglycemia), depending on how much you drink

Administration of SNAC to pregnant rats has shown an increase in number of stillbirths and a decrease in pup viability

It increased survival of cultured enteric neurons and proliferation of enteric glial cells, suggesting direct neuroprotective effects on the enteric nervous system that could influence central serotonin tone through vagal signaling