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Researchers initially investigated it as a potential treatment for obesity and metabolic disorders

The compound retains full GHRH receptor agonist activity despite lacking the C-terminal 15 residues of native GHRH, making it the shortest GHRH fragment with documented full intrinsic efficacy at the pituitary GHRH receptor (GHRHR)

Examples include sickle cell anemia (D57), hereditary spherocytosis (D58.0), and glucose-6-phosphate dehydrogenase deficiency (D55.0)