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A 2017 meta-analysis of randomised trials found significant reductions in fasting insulin and HOMA-IR with myo-inositol supplementation, alongside improvements in serum SHBG when taken for at least 24 weeks
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They found an increased risk of SPCs among men with prostate cancer, compared to the general population (SIR: 1.11, 95% CI: 1.061.17)
PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection
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