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In general, studies looking for associations between risk for atherosclerosis and polymorphisms or deficiencies in other major antioxidant genes including catalase, SOD-1, -2, and -3, and glutathione S-transferase have been negative (406,407)

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The Vasireddi et al

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Ferroptosis has been widely observed in small-molecule treated cells in vitro, and was implicated in various pathological conditions including neurodegeneration, ischemia/reperfusion-induced kidney, heart and liver injury, and stroke 2