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Levothyroxine pills are available in several different strengths, which your doctor can adjust based on factors such as: Age Weight The severity of thyroid disorder Other health problems Other medicines Once you start levothyroxine treatment, your doctor may order a thyroid-stimulating hormone (TSH) blood test to monitor your thyroid function

The standard dosage is 2,000 to 2,500 mcg of total blend injected subcutaneously once daily for 4 weeks, followed by 2 to 4 weeks off

Measure AMPK phosphorylation status in skeletal muscle or liver tissue to confirm MOTS-c activity this requires tissue biopsy and Western blot analysis

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