These uEVs are also a source of genetic markers, leading to their clinical use for diagnostics, as ExoDx Prostate Intelliscore, which detects prostate cancer gene signature of exosomal RNA: ERG, PCA3, SPDEF via RT-qPCR with a high sensitivity and negative predictive value [83]
In both *in vitro* models using hepatocyte cell lines (e.g., HepG2) and *in vivo* rodent models fed high-fat or methionine-choline deficient (MCD) diets, this formulation is used to investigate the mechanisms of hepatic steatosis
Available formulations include oral tablets, transdermal patches, topical gels, and sprays
PlexusDx ensures this relationship by requiring a complete medical history, current medication review, and contraindication screening before any prescription is issued
9 (download XLSX Statistical Source Data