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Again, in the first study using FOXO4-DRI to induce apoptosis in senescent cells, the senescent cells were generated by irradiation or doxorubicin ( As shown in Figure 3, FOXO4-DRI pre-treatment is the dedifferentiation of chondrocytes during the in vitro expansion

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Multi-omics analyses of Chinese medicine components allow researchers to identify potential biological targets and elucidate mechanisms of action, laying a scientific foundation for its modernization and global integration [639, 647, 648]

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