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Glycemic control in diabetes has been revolutionized with the recent widespread adoption of glucagon-like peptide-1 (GLP-1) receptor agonists

10.1097/01.hjh.0000500039.08261.4f 142 WanF.MaF.WuJ.QiaoX.ChenM.LiW.et al (2022)

The field needs validated, in vivocompatible flux sensors (O 2 , H 2 O 2 , NO/ONOO ) targeted to matrix/IMS, ER lumen, peroxisomes, plasma-membrane microdomains and nucleus, each with built-in specificity controls and reporting standards (matrix, oxygen tension, m, pH) to disambiguate signalling pulses from damage plateaus

Some cover, some dont, all worry about cost and whether its a sunk investment Hard to say

Yeo TW, Weinberg JB, Lampah DA, Kenangalem E, Bush P, Chen Y, Price RN, Young S, Zhang HY, Millington D, Granger DL, Anstey NM

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