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Ma S, et al

That is the whole story, start to finish: a stubborn idea from 1975, a researcher who spent his life on it, a compound that healed everything in rats, a human trial whose result nobody saw for twenty years, a molecule no company can own so no company will finish testing, and a stack of the most basic questions is it safe, at what dose, made by whom, and how does it actually work that still have no answers

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A typical loading approach might use 0.75mg to 1mg daily for the first 3 to 5 days, then reduce to 0.5mg for the remainder of the protocol

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doi: 10.1254/jphs.95.19