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In the trials of CONTRAVE, 4,536 patients from four different institutions were tested

There is currently no confirmed causal link between retatrutide and joint pain, as the drug remains unlicensed and Phase 3 trial data are still being collected

Individuals with high-risk conditions such as unstable angina, recent heart attacks within the past six months, severe thyroid disease, type 1 diabetes, or severe kidney or pancreatic disease should avoid using retatrutide

Explore This Issue June 2019 All of these drugs carry a warning regarding the possible association with medullary thyroid cancer (MTC) or multiple endocrine neoplasia syndrome 2 (MEN2)

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