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Retatrutide (LY3437943) simultaneously activates GLP-1, GIP, and glucagon receptors, distinguishing it from approved dual or single agonists such as tirzepatide and semaglutide

however, more pronounced benefits usually take a few months to become apparent

The commercial dosing may differ when the drug eventually launches

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Why Is Retatrutide Sometimes Called GLP-3 or GLP-R