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Such ratio significantly increased from baseline after 26 weeks of treatment with liraglutide 1.8 mg/day, indicating a reduction in liver steatosis, whereas it was unchanged in patients treated with lower doses of liraglutide, glimepiride or placebo

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Interestingly, metabolomic analysis in this study indicated that semaglutide treatment upregulated L-isoleucine and methacholine or downregulated L-histidinol, arachidonic acid, and 4,5- leukotriene (LT) A4 LysoPC(16:0), which are metabolites involved in the pathogenesis of NAFLD [32]

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He compares the brain's rhythm to musical harmony: if one beat is missed, the entire performance is affected