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Ahmed AE, Alsamghan A, Momenah MA, Alqhtani HA, Aldawood NA, Alshehri MA, Ali Alshehri AM, Alhag SK, Mosaad YO, Ahmed H

Clin Trans Immunol

This mechanism is primarily associated with inhibiting Mincle and its associated signaling components Syk and NF-B, which regulate macrophage polarizationspecifically reducing pro-inflammatory M1 phenotypes while enhancing anti-inflammatory M2 populations

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In the study, skin biopsy was used to establish the diagnosis of small-fiber neuropathy because of its high specificity, 91%, but it has lower sensitivity, 58% (Saltin et al., 1968