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Discard if it looks cloudy, discolored, or has particles

Formulas vary by category

In the liver, one of the enzymes under the cytochrome P450 oxidase enzyme family, CYP1A2 metabolizes caffeine into three primary metabolites: paraxanthine (84%), theobromine (12%) and theophylline (4%) (Schwarzschild et al., 2003)

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Context determines the best choice

You can adjust water volume for different concentrations, but this standard ratio simplifies calculations significantly