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Cross-linked antioxidant nanozymes for improved delivery to CNS

While there are available therapies for hyperphagia and hunger and, in fact, appetite reduction is a key effect of GLP-1 agonists, there are no significant available therapies that can address the decrease in energy expenditure [234]

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To test this prediction, we mutated VadK-His422 to alanine, checked that VadK His422Ala was folded in a similar manner to VadK WT by circular dichroism (CD) (Appendix Fig

It is the same active molecule used in some brand-name medications, taken as a once-weekly injection under provider supervision