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As we age or face environmental stress (sun, pollution, smoking), the bodys glutathione levels naturally fall, which can leave skin looking dull and tired

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Am J Physiol Gastrointest Liver Physiol 281(5):G1135G1139 Roman J, Colell A, Blasco C, Caballeria J, Pares A, Rodes J, Fernandez-Checa JC (1999) Differential role of ethanol and acetaldehyde in the induction of oxidative stress in HEP G2 cells: effect on transcription factors AP-1 and NF-kappaB