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The primary UK resource for finding eligible trials is the NIHR Be Part of Research portal (bepartofresearch.nihr.ac.uk), which lists NHS-supported studies

Plaintiffs point to pre-approval clinical trials and post-marketing adverse event reports that accumulated evidence of severe gastrointestinal complications years before manufacturers updated warning labels to reflect these serious risks

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Semaglutide might be better for those concerned about cost, side effects, or underlying metabolic conditions, given its longer real-world data and gentler side effect profile